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The major isomeric constituent of the QS-21 fraction. Now fully synthetic. Exceptional potency for humoral and cell-mediated immune responses.
≥95% purity via HPLC. Zero plant-derived impurities. Eliminate biological contaminants from your research.
Identical molecular structure every time. Ensure reproducible results in clinical trials with zero biological variation.
Not dependent on natural harvest. Scalable GMP production ensures reliable supply for global demand.
| Catalog Number | STR-QS21A-001 |
|---|---|
| CAS Number | 1450904-00-5 |
| Molecular Formula | C123H194O70 |
| Molecular Weight | ~1989 Da |
| Purity | ≥95% (HPLC) |
| Primary Function | Potent Immunostimulant |
| Solubility | Water-soluble (rec. PBS pH 7.4) |
| Storage | -20°C, protect from light/moisture |
| Appearance | White to off-white lyophilized powder |
| Grade | Research / GMP available |
GMP-grade material is produced under cGMP conditions and is accompanied by full documentation including a Drug Master File (DMF) submission. Contact us for GMP pricing and documentation.
Natural QS-21 is extracted from the bark of the Quillaja saponaria tree, a process subject to seasonal variability, supply chain fragility, and batch-to-batch inconsistency. Our synthetic QS-21-Api eliminates all of these risks.
| Attribute | Natural Extract | Synthetic (STR) |
|---|---|---|
| Purity | 70–85% | ≥95% |
| Batch consistency | Variable | Identical |
| Supply security | Seasonal / fragile | Year-round |
| Contaminants | Possible | None |
| Regulatory risk | Higher | Lower |
[Detailed Annotated Molecular Diagram]
Full structural data available in the Technical Data Sheet
Each batch undergoes comprehensive analytical characterization. Representative data packages include HPLC chromatograms, mass spectrometry, and NMR spectra.
Certificates of Analysis (CoA) are provided with every shipment. To request a CoA for a specific batch prior to ordering, use the button below.
Our adjuvants support research programs aligned with the most impactful vaccines in development.
STR Technologies adjuvants are used in research programs worldwide, including the development of vaccines aligned with Shingrix® (herpes zoster), Mosquirix® (malaria), and Covovax® (COVID-19) — all of which rely on QS-21-based adjuvant systems.
Explore our full range of synthetic vaccine adjuvants.
Our scientific team can help you find the right adjuvant for your research application.